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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f35e2b90c495edc77187240a752b4237fd077e0a994772ad647913043a8db8' 
  AND token = '8ZM7L6yrkVojRhdmJ13t42tMGBtPX7ywev/YtRwClV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}