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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ecfc4371e339fdc3b09335cc65a0ed763ffa160713b24f4d3621db9a2b95415' 
  AND token = '9tqn2GMYEe7Rr3Pi+1Kw6tHNhzB+c8RUMf6oigMLD7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}