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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e36d68b49151e4cd5b9ef1fdd66d668d634a12ceb0290e79ed68db2750f0b7c' 
  AND token = 'Ixxa50Z8RXYgKf+TS25PO9JI8ryAB/PFaYNyXXxAUcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}