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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60705f06f2b19b983e09978d6b001f6efa9fdae802369f2a5a7c75427ac0feb8' 
  AND token = 'DQL8MMEIZYuOmTowS/qgzHhB0B8D00YFutyZp1j8Rsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}