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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e573541dacf268b6bec4fcdeb8f79af8549f5394dc6b7b5c621f0b834dd3ab' 
  AND token = '2QXu5Rr59/5gzY/WzkngpPWrbOi/HLkTGs+aPxu0b44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}