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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd73777e469651d1caac1bf3110a6382fa828748d8ebcfc389397552b6c2f1c58' 
  AND token = 'udUyL0RIdSJI0SlEtPaRMGr4Q5DYZyBi7AGtMec8cUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}