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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43985565cb27a5ba5db8af1f103f2c81e92facabecd978a9faebae24c17dad8a' 
  AND token = 'GMRAy5XxKA/zzEZjiy9nkHuSdr+O04EZBxW+BEElSuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}