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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '066949fd4dd2709ebb8952f4c71528b90ef85d010fdcc656d654f48bd5ef074a' 
  AND token = 'lxJ9ckU3efLYkeO/hL/ObuoDseq5GwcOAgtAFySIcQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}