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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a69e0f87b78d68faefe3461ea77af8a8372a4980c49a16d28d23294e01eb829' 
  AND token = 'D0flojIwBZKgFfhP7XBSNtK0LZRHmInzmzEDXWnRKNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}