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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f3a866fc33266c868e47ca2c9b51ad61b140cb5e5fa86c28283e0ee2f937fc' 
  AND token = 'sEd4fQGWqURXaPFu2IBP+1mvrSjOiriVwUWgAD41Ue8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}