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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ebbc16382d6dc238a2b42f6fbf435fc035c32af9fa6e44165ff171076338679' 
  AND token = 'EoGwKVo8WraQfcRPDIK4PTwbI+uiRrukGyEL1Lka+d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}