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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa6be3e2b43f2536c953e3274c85b5330ba2efa9b4133e846d75446a63de4553' 
  AND token = 'sSuHelbkbyeO4ZinUtM51+MbK42udi2xbll4TUijNFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}