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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c6309183cc64bf069bd2160e894d812085ee87c32c7973c647957393af5e6d' 
  AND token = 'VeuVksJV5ExDxY6meLaK3BJ5xpDpVK6P/Mwd7XtDXck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}