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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8aa2c8d71be70ade778a8469c273ff84d7713d53b0f5004c8e77e508de00a8' 
  AND token = 'oew6+U7tP4s8MFfztVumghL/AKZHmXGNSoMFj9AsT8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}