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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d0cc8f6cd67b651c60c215f5d4c572ff38e489cfb1807bfa82791777f79dc2' 
  AND token = 'QsfqOyq+9Su4Hs92pUupf9YmSX+0njTL6PDS7wlnhyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}