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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0014663b78fe4ca5c16861100e11aee6e6f9b7f648e6ed2cafee38b256edd34' 
  AND token = 'H4kThFgsNon1OVLaJ6Sx2W+DcwBhBkiP8Cm84vfOzkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}