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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e833e02f404e82482c1384c1b640737963235069e7bb960da15f40d2253d3e7d' 
  AND token = 'HoNOFyNp66p/6LKMmUcL5p69vL0oOduO0VvQnQgVFVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}