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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253aac0b10125f3a899b503a05debcae3d67f6eb142b7b0fea09b96993d1d84f' 
  AND token = 'd6xwPfz3VV19VH/yLsUW4kCndYNbADKkRJnRDX/2hz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}