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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b1de054d8788b81fb7aa54f165211cf544f3a87550293522aa6f90156b33cf' 
  AND token = '3WeRA97oHV8wZUGJCXKFcafJWbntkl0bbTqgWGXTfoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}