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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'affd5c8d0393aa252643553f96a221c7aeee07e8267abcc9cbe6998fdd726ca4' 
  AND token = 'Nep8ZJcAWERv5WO9+hUiTf/j4W46/7M6o8T1ZxysVBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}