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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa44e8243832d1b0eff65e63542e8937c8915efc9a81e76720a2fbf1dffef1c7' 
  AND token = 'qBiIdDMGxL9bqEKtXFyes38OeKRPRNC9fkxJxjgNu0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}