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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4890b240eb6cd0a99cf43873e6f07c86b69607ca24b7e1bf9e75cababdae185f' 
  AND token = 'SOAEzwa2aCARvriiLofobODrYhuna8ntwrMLfPgK3X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}