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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0be636e8c31f84be521b46243585cd5e6504c8bb9bf161439b3debc9cd79cf6' 
  AND token = 'LQIzVVqJmvnWttBB/ZLTbs52ID8v/YcFkc21BUyrjZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}