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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22259d67e2946a178188c1dced593d7fda2c92379aa2f7e3ec9c0cd520f6bd29' 
  AND token = 'fu/08Nq07wKUyZzO9LJOCxsneh1OVLXW2b/hq5YIVsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}