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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f7fbd4480600f06aa1208aa8ce60aa8869385efd5f4bfcdcec318f134420ab' 
  AND token = 'zHWGW7jDf2FTvN838Afp93b7kCSA2I2nsDDyMQ2cPvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}