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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '054fc8317caae8d735afc178fa7b7502590d1bfeb4a50e053529f5bfda21f1d5' 
  AND token = 'vSKq8ELFyLdrPdCMh0SsIXsDQZUWD41LI8MTSpH54T4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}