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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fdcb584ab0783a2e737894d25c1adc5bf8d59b054e0527f0fee55701ca2da72' 
  AND token = 'etox+NAsgy/3K4c2P3D/z8J3jGRhfUv9SO05IqZPkL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}