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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06a6ad5682f3535e4ee1c954bc42b231700f6d376ea31686aec843d05445543b' 
  AND token = 'mJzx/MdtpaO//1f4D3tOfmYphtwYBDbgzsBPjFKb8wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}