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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19323ea3d50fac0a0c08d6f6c752dcaf6629fe00ace1d049cb85b82b8bcc439c' 
  AND token = 'neeUSlnETR0P+mt0WoKBhHnhjJ3Ygm6SMvWw5N4G6vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}