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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e087e6081456e04105385b415d1e383089aff30bdf89779f2a9b7fc50787727' 
  AND token = 'XSmNxZQ4cfPxraVgZI+BNCx69XZDp1kkNyci2qmpU1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}