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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac7fc104c8862647005b21e49b809d96d8e755acd3082944d83b8f12270a8c44' 
  AND token = 'NJNIsiIbcFA3jYMDGV2dfddB22GFOa0gSXjbuRn2JYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}