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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65799bfbcd6ac26daf9101122d9553567d4e3769c36ad2e1ddfff9edcf1b00d7' 
  AND token = 'JnJ8tTRKOkxWX86/GroTwgd6l42qAx+XCQ7FeTSL2SE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}