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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce37b48b56ffffff231690af17068c714f23ca11c1cb52363d0c3fb75cf9f70a' 
  AND token = 'HzA1Acn3BPvLoKhujiXbvycog1EQD5hdPR6H+NqVytc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}