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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80a6711df28419568abef0fc22cd8080e07c6b8b43ac51fd1d139793ff03e44' 
  AND token = 'qz1AFpMJ2vZwtYjg60s2t0lX1Qj4IFacJQon5b8nlN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}