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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6b0aef57a37cf756ffcc4731698f56d9b847809a3e0698750ad9ad5dc4d6f4' 
  AND token = 'vGwWD7L6XUZKDnkLC+YsPuy5jmDZE5af+/hf7485164=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}