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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591392e6a0f3783b3947795bcddb3863f484a5bc738eec99b7598683e92b5745' 
  AND token = 'pQkjW3VpCtFlbgvBKuY/fks7nAzsn7cfLXHtSbBtPc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}