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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01bc57e81acbe6be1700abbd13ec28adab03e34b7be1b3d77f67e8ac75f9cb4' 
  AND token = 'w5nioOJC8r6MF0Lt8MQTXKSwjdK8pV/Qxf/MrmnBMmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}