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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8c7687a0419e9f9312e4f0af8b108273b85b812c6f00959af74921edee3a03' 
  AND token = 'c1dFmENjbUcsTrtkG4WKNBay4PqA+4GJNrKBCQDtFNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}