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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780c052e5be4b3be015fa48a1f6d351ee24a96eecf3e237c35edb509ffe3e5e8' 
  AND token = 'f1Uz23OhBxUGwxDoivgRF3wu3iDecrC+uxM0F8hUAoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}