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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46154afbdc19d733895f5fcffdac6bc98206cb6b1c1d08bba87831549e6d63ea' 
  AND token = 'S0bVVupSwGIJe9nbYkcXZYuw++S2rZKUwMJ/IA12M8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}