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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4270f6e122e0100dbebfe0c9d24382f9955f0aadb41aaed3a84f88cb2f0f66' 
  AND token = 'xot/lRDr48xm6iDKGD9bwIEE7ddY6P/suSCrxa8eEEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}