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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d272afdcf341b8de09338218729c22c507da95dde6f21659c2df98cfed36ce' 
  AND token = 'Hu1MMgpyprVO6VRMCuQZ5CYkERLZssG9InAm+75ng1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}