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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5f106c03c7af216d986c4024cd2c8285b23b7b5792e231e8e20fc819651f1d' 
  AND token = 'S0yocdL3TpuxxHI5fi+96PLx1+liBpa6cfBEfpNWdJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}