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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdd9116823b710953412607f8a58e73e8226ba0b901d0b1e1c72a0c7048995e2' 
  AND token = 'Eec5sSz85nBOd7jdlX1xeKbJBfJij/2q4/UhXgNI0wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}