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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e34761e3dee27528cc92f4b73146e0407201ce1abe8b0b3002c6cc841f3d0a' 
  AND token = 'kR5hc5D33+8Gn9UQtkFq+CUSKXgHW13MJiRLADVXQdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}