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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e262341678e24353612530a91bbd47a5d28136a4b8eebd11b643ed59313fe7' 
  AND token = 'GqMJrJ4Jzu57PiFsZoqOceSnMVffZaW2DNSQ/T/HudE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}