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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd495d95682853000b3216e87b7c0bca6dc6f57d5f3e4763ae4144b53c3ef165' 
  AND token = 'K6XJcce//Ee3PYAN2h5gDTI2q36a5XbqYgvVTts6bOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}