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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14612978a283e42101b9e8c858a32774a2c66302a2d3bf67c3e66c3dd744e54e' 
  AND token = 'faFC8U5VgMFPn5554wm6RX5px9UE/1BaEk15MxKlYCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}