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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87d2da91a02417e2c1da75777cffbe8fcae4cabe47aae5ee29504e4ba12f5fab' 
  AND token = 'LRyApnELI1TeIxqyPUBUki505iW6NtE5yCQ4TN/VmDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}