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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e78180e26563107ede4223ed8b1d10880c150c546d7bc57f849fcc6810ef8c' 
  AND token = '1EwVsR0LT5HMMvuNp7wz0Q1OfzEZ5+s4W5FlHEk0tAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}